SCHEMBL8673129

SCHEMBL8673129

Cc1cc(C)cc(OCCOCCOc2cc(C)cc(C)c2)c1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.47
ALOX15 P16050 1/20 0.47
MAPK1 P28482 3/20 0.45
TDP1 Q9NUW8 3/20 0.43
KDM4E B2RXH2 2/20 0.43
MAPT P10636 2/20 0.41
LMNA P02545 1/20 0.41
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
RAB9A P51151 2/20 0.40
NPC1 O15118 2/20 0.40
ALDH1A1 P00352 2/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8672402 1.00 TP53 (0.47) TP53ALOX15MAPK1TDP1KDM4E
SCHEMBL5929477 0.92 TP53 (0.52) TP53ALOX15MAPK1TDP1KDM4E
SCHEMBL13021583 0.91 MEN1 (0.45) TP53ALOX15MAPK1TDP1KDM4E
SCHEMBL15532948 0.89 TP53 (0.41) TP53ALOX15MAPK1TDP1KDM4E
SCHEMBL9770294 0.89 NCF1 (0.44) TP53ALOX15MAPK1TDP1KDM4E
SCHEMBL13413138 0.87 KDM4E (0.42) TP53ALOX15MAPK1TDP1KDM4E
SCHEMBL9308498 0.85 TP53 (0.49) TP53ALOX15MAPK1LMNAMEN1
SCHEMBL3440051 0.83 MEN1 (0.49) TP53ALOX15MAPK1TDP1KDM4E
SCHEMBL12749081 0.82 TP53 (0.63) TP53ALOX15MAPK1TDP1KDM4E
SCHEMBL15532139 0.82 ABCG2 (0.49) TP53ALOX15MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5827796-A Thermal recording material FUJI PHOTO FILM CO., LTD. (JP) 1998-10-27 US disclosed
US-4981836-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1991-01-01 US disclosed
US-4855278-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1989-08-08 US disclosed
US-4835133-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1989-05-30 US disclosed