Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.43 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.41 |
| ▸ | GRIK4 | Q16099 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8672915 | 0.84 | GRIK1 (0.39) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8675868 | 0.83 | GRIA1 (0.53) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8674016 | 0.83 | GRIA1 (0.64) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8611345 | 0.82 | GRIK1 (0.57) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8610303 | 0.81 | GRIK1 (0.41) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8611525 | 0.78 | GRIK1 (0.57) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8612845 | 0.78 | OPRM1 (0.39) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8612024 | 0.78 | OPRL1 (0.48) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8609461 | 0.77 | GRIK1 (0.61) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8611278 | 0.76 | GRIK1 (0.47) | GRIK1GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849743-A | Quinoxalines and drugs prepared therefrom | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| WO-1996019476-A1 | NOVEL QUINOXALINES AND DRUGS PREPARED THEREFROM | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-27 | — | — | WO | disclosed |