Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 5/20 | 0.53 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.53 |
| ▸ | GRIA3 | P42263 | 5/20 | 0.53 |
| ▸ | GRIA4 | P48058 | 5/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.53 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.53 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.53 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.53 |
| ▸ | GRIK4 | Q16099 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8672915 | 0.86 | GRIK1 (0.39) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8674102 | 0.86 | GRIA1 (0.72) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8673142 | 0.83 | GRIK1 (0.43) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8675985 | 0.79 | GRIA1 (0.71) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8674811 | 0.78 | GRIA1 (0.61) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7480931 | 0.78 | GRIA1 (0.61) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8610303 | 0.78 | GRIK1 (0.41) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8612845 | 0.75 | OPRM1 (0.39) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8611345 | 0.74 | GRIK1 (0.57) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7665623 | 0.72 | GRIA1 (0.66) | GRIA1GRIA2GRIA3GRIA4GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849743-A | Quinoxalines and drugs prepared therefrom | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |