SCHEMBL8673159

SCHEMBL8673159

[CH2]CC=C(CC=C)CC=C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9579048 0.84
SCHEMBL8673205 0.77
SCHEMBL7638570 0.75 TSHR (0.32) TSHR
SCHEMBL6677303 0.75 TSHR (0.47) TSHR
SCHEMBL278195 0.73 ALDH1A1 (0.44) TSHR
SCHEMBL14759568 0.73
SCHEMBL8846297 0.73
SCHEMBL7196179 0.73 TSHR (0.30) TSHR
SCHEMBL7676124 0.73 ALDH1A1 (0.35) TSHR
SCHEMBL9879515 0.73 TSHR (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5811422-A USEFUL FOR TREATING VIRAL INFECTIONS THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1998-09-22 US disclosed
US-5610294-A VIRAL TREATMENT THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1997-03-11 US disclosed