Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677297 | 0.86 | TSHR (0.33) | TSHR | |
| SCHEMBL6677303 | 0.75 | TSHR (0.47) | TSHR | |
| SCHEMBL8673159 | 0.75 | TSHR (0.32) | TSHR | |
| SCHEMBL8767073 | 0.73 | — | — | |
| SCHEMBL8767075 | 0.73 | — | — | |
| SCHEMBL7676124 | 0.73 | ALDH1A1 (0.35) | TSHR | |
| SCHEMBL7196179 | 0.73 | TSHR (0.30) | TSHR | |
| SCHEMBL846615 | 0.73 | — | — | |
| SCHEMBL278195 | 0.73 | ALDH1A1 (0.44) | TSHR | |
| SCHEMBL9879515 | 0.73 | TSHR (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3966187-A1 | PROMOTERS FOR HETEROGENEOUS OLEFIN METATHESIS | Massachusetts Institute of Technology (US) | 2022-03-16 | — | — | EP | claimed |
| WO-2020227616-A1 | PROMOTERS FOR HETEROGENEOUS OLEFIN METATHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-11-12 | — | — | WO | claimed |
| US-20200354291-A1 | PROMOTERS FOR HETEROGENEOUS OLEFIN METATHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-11-12 | — | — | US | claimed |
| CN-114981319-A | Polyvinyl alcohol resin, method for producing polyvinyl alcohol resin, dispersant, and dispersant for suspension polymerization | 三菱化学株式会社 | 2022-08-30 | — | — | CN | disclosed |
| EP-3966187-A1 | PROMOTERS FOR HETEROGENEOUS OLEFIN METATHESIS | Massachusetts Institute of Technology (US) | 2022-03-16 | — | — | EP | disclosed |
| CN-113544163-A | Polyvinyl alcohol resin, method for producing polyvinyl alcohol resin, dispersant, and dispersant for suspension polymerization | 三菱化学株式会社 | 2021-10-22 | — | — | CN | disclosed |
| US-20200354291-A1 | PROMOTERS FOR HETEROGENEOUS OLEFIN METATHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-11-12 | — | — | US | disclosed |
| WO-2020227616-A1 | PROMOTERS FOR HETEROGENEOUS OLEFIN METATHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-11-12 | — | — | WO | disclosed |
| US-20020019429-A1 | Metalloproteinase inhibitors, pharmaceutical compositions containing them, and their use | BENDER STEVEN L (US) | 2002-02-14 | — | — | US | disclosed |
| US-6306892-B1 | ENZYME INHIBITORS HETEROCYCLIC AMIDES | AGOURON PHARMACEUTICALS, INC. | 2001-10-23 | — | — | US | disclosed |
| US-6174915-B1 | FOR TREATING MAMMALIAN DISEASE CONDITION MEDIATED BY METALLOPROTEINASE ACTIVITY | AGOURON PHARMACEUTICALS, INC. | 2001-01-16 | — | — | US | disclosed |
| US-4705847-A | Polycycloalkylidene-polycycloalkanes, epidioxy derivatives thereof and method of preparation | AKZO N.V. (NL) | 1987-11-10 | — | — | US | disclosed |
| EP-0106863-B1 | A PROCESS FOR PREPARING SUBSTITUTED POLYCYCLO-ALKYLIDENE POLYCYCLO-ALKANES AS WELL AS SAID SUBSTITUTED POLYCYCLO-ALKYLIDENE POLYCYCLO-ALKANES | RIJKSUNIVERSITEIT TE GRONINGEN (NL) | 1986-08-20 | — | — | EP | disclosed |
| US-4511753-A | Selective removal of vinylidene olefin from olefin mixtures | ETHYL CORPORATION (US) | 1985-04-16 | — | — | US | disclosed |
| EP-0106863-A1 | A PROCESS FOR PREPARING SUBSTITUTED POLYCYCLO-ALKYLIDENE POLYCYCLO-ALKANES AS WELL AS SAID SUBSTITUTED POLYCYCLO-ALKYLIDENE POLYCYCLO-ALKANES. | UNIV GRONINGEN (NL) | 1984-05-02 | — | — | EP | disclosed |
| WO-1983003604-A1 | A PROCESS FOR PREPARING SUBSTITUTED POLYCYCLO-ALKYLIDENE POLYCYCLO-ALKANES AND THE CORRESPONDING EPIDIOXY COMPOUNDS; AS WELL AS SAID SUBSTITUTED POLYCYCLO-ALKYLIDENE POLYCYCLO-ALKANES AND THE CORRESPONDING EPIDIOXY COMPOUNDS | HUMMELEN, JAN, CORNELIS | 1983-10-27 | — | — | WO | disclosed |
| EP-0081509-A4 | VINYL GUM CURE ACCELERATORS FOR ADDITION-CURE SILICONE. | GEN ELECTRIC (US) | 1983-07-26 | — | — | EP | disclosed |
| EP-0081509-A1 | VINYL GUM CURE ACCELERATORS FOR ADDITION-CURE SILICONE. | GEN ELECTRIC (US) | 1983-06-22 | — | — | EP | disclosed |
| WO-1982004013-A1 | VINYL GUM CURE ACCELERATORS FOR ADDITION-CURE SILICONE | GEN ELECTRIC (US) | 1982-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019429-A1 | Metalloproteinase inhibitors, pharmaceutical compositions containing them, and their use | MMP9, MMP2, MMP3 | TSHR 3670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.