Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL977650 | 0.81 | CAPN1 (0.57) | CAPN1TSHRCA1CA2L3MBTL1 | |
| SCHEMBL3109472 | 0.81 | CAPN1 (0.57) | CAPN1TSHRCA1CA2L3MBTL1 | |
| SCHEMBL8971238 | 0.78 | ALDH1A1 (0.73) | CAPN1LMNAHPGDALDH1A1MAPT | |
| SCHEMBL5364748 | 0.78 | HPGD (0.78) | CAPN1CA1CA2L3MBTL1LMNA | |
| SCHEMBL9281958 | 0.77 | MAPT (0.46) | CAPN1L3MBTL1LMNAGAAHPGD | |
| SCHEMBL23003 | 0.76 | TSHR (0.79) | CAPN1TSHRCA1CA2ALDH1A1 | |
| SCHEMBL1247034 | 0.76 | TSHR (0.61) | CAPN1TSHRCA1CA2L3MBTL1 | |
| SCHEMBL7786977 | 0.76 | CAPN1 (1.00) | CAPN1 | |
| SCHEMBL7379589 | 0.76 | CAPN1 (1.00) | CAPN1 | |
| SCHEMBL28903966 | 0.75 | CAPN1 (0.52) | CAPN1TSHRCA1CA2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128488-A | Phosphorus-metal complex catalyst | SOCIETE CHIMIQUE DES CHARBONNAGES S.A. (FR) | 1992-07-07 | — | — | US | claimed |
| EP-0253700-B1 | PROCESS FOR THE ASYMMETRIC HYDROGENATION OF CARBONYL COMPOUNDS, AND THE COMPOUNDS OBTAINED THEREBY | ELF ATOCHEM S.A. (FR) | 1990-08-29 | — | — | EP | claimed |
| US-5834588-A | (Cyanomethylene) phosphoranes as carbonyl 1,1-dipole synthons for use in constructing combinatorial libraries | YALE UNIVERSITY (US) | 1998-11-10 | — | — | US | disclosed |
| EP-0443923-B1 | New aminophosphine-phosphinites, their process and their use for enantio-selective reactions | SANOFI SA (FR) | 1997-08-27 | — | — | EP | disclosed |
| US-5128488-A | Phosphorus-metal complex catalyst | SOCIETE CHIMIQUE DES CHARBONNAGES S.A. (FR) | 1992-07-07 | — | — | US | disclosed |
| EP-0443923-A1 | New aminophosphine-phosphinites, their process and their use for enantio-selective reactions | SANOFI (FR) | 1991-08-28 | — | — | EP | disclosed |
| EP-0253700-B1 | PROCESS FOR THE ASYMMETRIC HYDROGENATION OF CARBONYL COMPOUNDS, AND THE COMPOUNDS OBTAINED THEREBY | ELF ATOCHEM S.A. (FR) | 1990-08-29 | — | — | EP | disclosed |
| EP-0253700-A1 | Process for the asymmetric hydrogenation of carbonyl compounds, and the compounds obtained thereby | ELF ATOCHEM S.A. (FR) | 1988-01-20 | — | — | EP | disclosed |
| WO-1987007889-A1 | ASYMETRIC HYDROGENATION PROCESS FOR CARBONYL COMPOUNDS, AND COMPOUNDS OBTAINED | SOCIETE CHIMIQUE DES CHARBONNAGES S.A. (FR) | 1987-12-30 | — | — | WO | disclosed |