Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024877 | 0.78 | CYP1A2 (0.32) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8024841 | 0.72 | KDM4E (0.33) | KDM4EMEN1ALOX15KMT2AHSD17B10 | |
| Bromide SCHEMBL8038473 | 0.72 | KDM4E (0.33) | KDM4EMEN1ALOX15KMT2AHSD17B10 | |
| SCHEMBL8024847 | 0.69 | — | — | |
| SCHEMBL8038477 | 0.69 | — | — | |
| SCHEMBL12657230 | 0.62 | HTR2A (0.33) | — | |
| SCHEMBL7759390 | 0.60 | — | — | |
| Bromide SCHEMBL29115028 | 0.60 | TSHR (0.43) | KDM4E | |
| Bromide SCHEMBL27725793 | 0.60 | TSHR (0.43) | KDM4E | |
| SCHEMBL5494672 | 0.57 | TSHR (0.45) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721327-A | Process for the preparation of crystalline vinylaromatic polymers with a predominant syndiotactic structure | ENICHEM S.P.A. (IT) | 1998-02-24 | — | — | US | disclosed |
| EP-0796875-A2 | Process for the preparation of crystalline vinylaromatic polymers with a predominant syndiotactic structure | ENICHEM S.p.A. (IT) | 1997-09-24 | — | — | EP | disclosed |