Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37955 | 1.00 | TSHR (0.45) | TSHRCYP1A2CYP2A6TDP2NSD2 | |
| SCHEMBL5181689 | 0.95 | TSHR (0.43) | TSHRCYP1A2CYP2A6TDP2NSD2 | |
| SCHEMBL10346182 | 0.95 | TSHR (0.43) | TSHRCYP1A2CYP2A6TDP2NSD2 | |
| SCHEMBL571577 | 0.95 | TSHR (0.43) | TSHRCYP1A2CYP2A6TDP2NSD2 | |
| SCHEMBL4699685 | 0.88 | ALDH1A1 (0.45) | TSHRCYP1A2CYP2A6TDP2NSD2 | |
| SCHEMBL23854312 | 0.84 | POLB (0.55) | TSHRCYP1A2CYP2A6TDP2NSD2 | |
| SCHEMBL4078654 | 0.84 | TSHR (0.38) | TSHRCYP1A2CYP2A6TDP2NSD2 | |
| SCHEMBL4071459 | 0.84 | TRPA1 (0.55) | TSHRCYP1A2CYP2A6ACHETRPA1 | |
| SCHEMBL31673873 | 0.84 | POLB (0.55) | TSHRCYP1A2CYP2A6TDP2NSD2 | |
| Ethylenediamine SCHEMBL18725865 | 0.82 | TAAR1 (0.42) | TSHRCYP1A2CYP2A6TDP2NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120202766-A1 | N4-ACYLCYTOSINE NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS | PHARMASSET, INC. (US) | 2012-08-09 | — | — | US | disclosed |
| US-20070078080-A1 | N4-Acylcytosine Nucleosides for Treatment of Viral Infections | GILEAD PHARMASSET LLC | 2007-04-05 | — | — | US | disclosed |
| US-4778946-A | DESORPTION WITH AROMATIC HYDROCARBON | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1988-10-18 | — | — | US | disclosed |
| EP-0105698-A1 | A process for separating ethylbenzene from feedstream containing meta-xylene using a zeolite adsorbent | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1984-04-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078080-A1 | N4-Acylcytosine Nucleosides for Treatment of Viral Infections | ENTPD5, DUT, NT5C3B | TSHR 4176/4885CYP1A2 1240/4885CYP2A6 1327/4885 |
| US-20120202766-A1 | N4-ACYLCYTOSINE NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS | ENTPD5, DUT, NT5C3B | TSHR 4165/4885CYP1A2 1174/4885CYP2A6 1296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.