Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.30 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8673516 | 0.90 | METAP2 (0.38) | METAP2BRD4GRM2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL8674093 | 0.85 | METAP2 (0.34) | METAP2BRD4GRM2TRPV1HTR2A | |
| SCHEMBL8677925 | 0.84 | BRD4 (0.35) | METAP2BRD4GRM2TSHRAVPR2 | |
| SCHEMBL8675208 | 0.82 | TSHR (0.32) | TRPV1HTR2AHTR2CHTR2BTSHR | |
| SCHEMBL8674269 | 0.82 | BRD4 (0.34) | METAP2BRD4GRM2TSHRAVPR2 | |
| SCHEMBL8673507 | 0.81 | BRD4 (0.36) | METAP2BRD4GRM2AVPR2AVPR1A | |
| SCHEMBL8677348 | 0.78 | P2RX7 (0.32) | — | |
| SCHEMBL8673551 | 0.76 | METAP2 (0.37) | METAP2BRD4GRM2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL8673519 | 0.75 | METAP2 (0.38) | METAP2BRD4GRM2HTR2AHTR2C | |
| SCHEMBL138026 | 0.74 | CNR2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840947-A | Organometallic compound | TARGOR GMBH (DE) | 1998-11-24 | — | — | US | claimed |
| US-5840947-A | Organometallic compound | TARGOR GMBH (DE) | 1998-11-24 | — | — | US | disclosed |