Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1537237 | 0.88 | CA12 (0.48) | LMNACA12CA1CA2CA9 | |
| SCHEMBL8672698 | 0.85 | SLC6A3 (0.55) | SLC6A3SLC6A2SLC6A4LMNAGPBAR1 | |
| SCHEMBL2203786 | 0.81 | CYP2C19 (0.56) | SLC6A3SLC6A2SLC6A4LMNAEPHX2 | |
| SCHEMBL10957432 | 0.78 | IDO1 (0.47) | SLC6A3SLC6A2SLC6A4LMNAALDH1A1 | |
| SCHEMBL11363849 | 0.77 | SLC6A2 (0.47) | SLC6A3SLC6A2SLC6A4LMNAGPBAR1 | |
| SCHEMBL170301 | 0.77 | SLC6A2 (0.55) | SLC6A3SLC6A2SLC6A4LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL128794 | 0.76 | SLC6A2 (0.53) | SLC6A3SLC6A2SLC6A4LMNAALDH1A1 | |
| SCHEMBL8672694 | 0.74 | SLC6A2 (0.52) | SLC6A3SLC6A2SLC6A4LMNAALDH1A1 | |
| SCHEMBL3400559 | 0.74 | HTR2A (0.73) | SLC6A3SLC6A2SLC6A4ALDH1A1POLB | |
| SCHEMBL8611125 | 0.74 | MEN1 (0.47) | LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719168-A | Acetamide derivatives and their use as feeding behaviour modifiers | LABORATOIRE L. LAFON (FR) | 1998-02-17 | — | — | US | disclosed |