Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20209401 | 0.77 | CYP1A2 (0.35) | CYP3A4TSHR | |
| SCHEMBL30365719 | 0.75 | ADRA2A (0.36) | CYP3A4TSHR | |
| SCHEMBL50690 | 0.75 | ADRA2A (0.36) | CYP3A4TSHR | |
| SCHEMBL29352264 | 0.75 | ADRA2A (0.36) | CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL28386300 | 0.73 | ADRA2A (0.35) | CYP3A4TSHR | |
| SCHEMBL1856199 | 0.73 | CYP3A4 (0.31) | CYP3A4TSHR | |
| SCHEMBL22283312 | 0.73 | CYP3A4 (0.31) | CYP3A4TSHR | |
| SCHEMBL417512 | 0.72 | CYP3A4 (0.30) | CYP3A4TSHR | |
| SCHEMBL11795000 | 0.71 | MTNR1A (0.30) | — | |
| SCHEMBL14975752 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726322-A | 1-benzenesulfonyl-1,3-dihydroindol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present | SANOFI (FR) | 1998-03-10 | — | — | US | disclosed |