SCHEMBL8674489

SCHEMBL8674489

NCC(C(=O)O)P(=O)(O)O

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 8/20 0.54
GABBR2 O75899 1/20 0.48
GABBR1 Q9UBS5 1/20 0.48
ANPEP P15144 1/20 0.46
ERAP2 Q6P179 1/20 0.46
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
BLM P54132 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GLUL P15104 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6882285 0.80 FOLH1 (0.61) FOLH1GABBR2GABBR1LMNABLM
SCHEMBL8532031 0.78 FOLH1 (0.58) FOLH1MEN1LMNAHPGDTSHR
SCHEMBL4726591 0.77 FOLH1 (0.57) FOLH1LMNABLMGLUL
SCHEMBL7049234 0.76 FOLH1 (0.56) FOLH1GABBR2GABBR1MEN1LMNA
SCHEMBL1960686 0.74 FOLH1 (0.54) FOLH1MEN1LMNAHPGDTSHR
SCHEMBL9639354 0.74 FOLH1 (0.54) FOLH1MEN1LMNAHPGDTSHR
SCHEMBL10624719 0.74 FOLH1 (0.67) FOLH1MEN1LMNAHPGDTSHR
SCHEMBL1561758 0.74 FOLH1 (0.60) FOLH1MEN1LMNAHPGDTSHR
SCHEMBL10702069 0.72 FOLH1 (0.64) FOLH1MEN1LMNAHPGDTSHR
SCHEMBL10788170 0.72 FOLH1 (0.52) FOLH1MEN1LMNAHPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5723645-A REACTION OF AMINOPROPANOL WITH PHOSPHORUS OXYCHLORIDE, HYDROLYSIS AND CRYSTALLIZATION PACIFIC CORPORATION (KR) 1998-03-03 US disclosed