SCHEMBL4726591

SCHEMBL4726591

NCCCC(C(=O)O)P(=O)(O)O

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.57
CPB2 Q96IY4 3/20 0.45
LMNA P02545 1/20 0.44
CYP3A4 P08684 1/20 0.44
NFKB1 P19838 1/20 0.44
BLM P54132 1/20 0.44
PMP22 Q01453 1/20 0.44
GSR P00390 1/20 0.43
RNPEP Q9H4A4 1/20 0.42
GLUL P15104 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6882285 0.86 FOLH1 (0.61) FOLH1LMNACYP3A4NFKB1BLM
SCHEMBL10624719 0.86 FOLH1 (0.67) FOLH1LMNABLMGLUL
SCHEMBL21611882 0.80 FOLH1 (0.59) FOLH1LMNACYP3A4NFKB1BLM
SCHEMBL9461890 0.78 FOLH1 (0.76) FOLH1LMNA
SCHEMBL3232568 0.78 FOLH1 (0.57) FOLH1
SCHEMBL11396532 0.77 FOLH1 (0.73) FOLH1LMNANFKB1PMP22
SCHEMBL389804 0.77 FDPS (0.57) FOLH1
SCHEMBL8674489 0.77 FOLH1 (0.54) FOLH1LMNABLMGLUL
SCHEMBL9487038 0.75 FDPS (0.59) FOLH1
SCHEMBL3377184 0.75 FDPS (0.59) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008002594-A2 NEURONAL CIRCUIT-DEPENDENT NEUROPROTECTION BY INTERACTION BETWEEN NICOTINIC RECEPTORS NEUROPROTECTION FOR LIFE CORP. (PR) 2008-01-03 WO disclosed