SCHEMBL8674802

SCHEMBL8674802

CC[C@H](O)N(N)CCCO

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9193301 0.78
Bromide SCHEMBL15826378 0.74 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL15826661 0.74 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2
SCHEMBL16105446 0.74 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2
SCHEMBL9192262 0.73
SCHEMBL16105557 0.73 ALDH1A1 (0.32) ALDH1A1SMN1; SMN2
SCHEMBL28918655 0.70 SMN1; SMN2 (0.38) ALDH1A1SMN1; SMN2
Acetic Acid SCHEMBL15826261 0.68 CAMK2A (0.30)
SCHEMBL4330063 0.66 TSHR (0.39)
SCHEMBL6565224 0.65 MAPT (0.36) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0874847-A1 NOVEL PURINE DERIVATIVES HAVING, IN PARTICULAR, ANTIPROLIFERATIVE PROPERTIES, AND BIOLOGICAL USES THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1998-11-04 EP disclosed
WO-1997020842-A1 NOVEL PURINE DERIVATIVES HAVING, IN PARTICULAR, ANTIPROLIFERATIVE PROPERTIES, AND BIOLOGICAL USES THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 1997-06-12 WO disclosed