Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | TYR | P14679 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8677218 | 0.88 | PTGER1 (0.49) | NPC1RAB9APTGER1PTGER4PTGER3 | |
| SCHEMBL8676527 | 0.88 | PTGER1 (0.49) | NPC1RAB9APTGER1PTGER4PTGER3 | |
| SCHEMBL8677032 | 0.86 | ABCB1 (0.63) | HTR1ADRD2MRGPRX4ABCB1KMT2A | |
| SCHEMBL8676624 | 0.86 | MRGPRX4 (0.48) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL8676622 | 0.83 | RAB9A (0.68) | NPC1RAB9AKMT2A | |
| SCHEMBL10980613 | 0.83 | ESR1 (0.69) | NPC1RAB9ATYRESR1ESR2 | |
| SCHEMBL8676387 | 0.82 | PTGER1 (0.62) | NPC1RAB9APTGER1PTGER4PTGER3 | |
| SCHEMBL8675525 | 0.81 | PTGER1 (0.61) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL8679134 | 0.81 | MEN1 (0.50) | RAB9APTGER1KMT2ATDP1 | |
| SCHEMBL6287279 | 0.79 | MRGPRX4 (0.51) | NPC1RAB9APTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |