Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.48 |
| ▸ | PPIA | P62937 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674872 | 0.86 | NPC1 (0.54) | MRGPRX4PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8677032 | 0.84 | ABCB1 (0.63) | MRGPRX4HTR1ADRD2ABCB1KMT2A | |
| SCHEMBL8676527 | 0.84 | PTGER1 (0.49) | MRGPRX4PPIAPTGER1PTGER4PTGER3 | |
| SCHEMBL8677218 | 0.84 | PTGER1 (0.49) | MRGPRX4PPIAPTGER1PTGER4PTGER3 | |
| SCHEMBL8676445 | 0.83 | MRGPRX4 (0.47) | MRGPRX4PPIAPTGER1PTGER4PTGER3 | |
| SCHEMBL6330377 | 0.82 | TDP1 (0.63) | VNN1SLC6A2SLC6A3KMT2ATDP1 | |
| SCHEMBL8676387 | 0.81 | PTGER1 (0.62) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL8675525 | 0.80 | PTGER1 (0.61) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL8676622 | 0.80 | RAB9A (0.68) | PPIAKMT2A | |
| SCHEMBL8679134 | 0.77 | MEN1 (0.50) | PPIAPTGER1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |