Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 4/20 | 0.57 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.57 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.57 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.52 |
| ▸ | CDK1 | P06493 | 1/20 | 0.52 |
| ▸ | CDK4 | P11802 | 1/20 | 0.52 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.52 |
| ▸ | CCND1 | P24385 | 1/20 | 0.52 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8675280 | 0.86 | PTGER1 (0.59) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL8674679 | 0.85 | PTGER4 (0.57) | PTGER1PTGER4PTGER3PTGER2NPC1 | |
| SCHEMBL8674848 | 0.85 | PTGER1 (0.57) | PTGER1PTGER4PTGER3PTGER2NPC1 | |
| SCHEMBL8674858 | 0.85 | PTGER1 (0.57) | PTGER1PTGER4PTGER3PTGER2NPC1 | |
| SCHEMBL8675797 | 0.82 | PTGER1 (0.63) | PTGER1PTGER4PTGER3PTGER2NPC1 | |
| SCHEMBL8677553 | 0.79 | PTGER1 (0.59) | PTGER1PTGER4PTGER3PTGER2NPC1 | |
| SCHEMBL8674885 | 0.77 | PTGER1 (0.66) | PTGER1PTGER4PTGER3PTGER2NPC1 | |
| SCHEMBL8675099 | 0.76 | PTGER1 (0.55) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL6470514 | 0.76 | PTGER1 (0.59) | PTGER1NPC1MRGPRX4MAPTDHODH | |
| SCHEMBL112903 | 0.73 | SGMS2 (0.66) | PTGER1NPC1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |