Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8673177 | 0.77 | LMNA (0.35) | LMNAGAATSHRCYP2C19BACE1 | |
| SCHEMBL8678113 | 0.72 | LMNA (0.38) | LMNAGAAMEN1ALDH1A1POLB | |
| SCHEMBL8675369 | 0.70 | LMNA (0.36) | LMNAGAAMEN1ALDH1A1POLB | |
| SCHEMBL29080999 | 0.70 | MEN1 (0.38) | MEN1 | |
| SCHEMBL8676257 | 0.66 | GAA (0.38) | LMNAGAAMEN1ALDH1A1POLB | |
| SCHEMBL8673707 | 0.64 | LMNA (0.36) | LMNAGAAMEN1ALDH1A1POLB | |
| SCHEMBL1861291 | 0.63 | CYP3A4 (0.39) | LMNAMEN1ALDH1A1POLBKMT2A | |
| SCHEMBL822450 | 0.62 | LMNA (0.42) | LMNAGAAMEN1ALDH1A1POLB | |
| SCHEMBL32689845 | 0.62 | KMT2A (0.42) | LMNAGAAMEN1ALDH1A1POLB | |
| SCHEMBL8819311 | 0.62 | HTR2A (0.38) | LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814324-A | OIL IN WATER EMULSION COMPRISING ANTIFUNGAL TRIAZOLE COMPOUND DISPERSED IN WATER WITH FATTY ACID TRIGLYCERIDE, LECITHIN EMULSIFIER | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-29 | — | — | US | disclosed |
| CN-1106390-A | Azole compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-08-09 | — | — | CN | disclosed |