Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8675159 | 0.77 | LMNA (0.35) | LMNAGAACYP2C19TSHRBACE1 | |
| SCHEMBL8676257 | 0.72 | GAA (0.38) | LMNAGAACYP2C19TSHRBACE1 | |
| SCHEMBL8678113 | 0.66 | LMNA (0.38) | LMNAGAAEGFRGABRA1GABRG2 | |
| SCHEMBL8675369 | 0.64 | LMNA (0.36) | LMNAGAAEGFR | |
| SCHEMBL32689845 | 0.62 | KMT2A (0.42) | LMNAGAACYP2C19TSHRBACE1 | |
| SCHEMBL822450 | 0.62 | LMNA (0.42) | LMNAGAACYP2C19TSHREGFR | |
| SCHEMBL3613976 | 0.62 | GAA (0.37) | LMNAGAATSHREGFR | |
| SCHEMBL9540089 | 0.61 | ADAM17 (0.46) | ADAM17 | |
| SCHEMBL8673707 | 0.61 | LMNA (0.36) | LMNAGAAEGFR | |
| SCHEMBL29080999 | 0.61 | MEN1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814324-A | OIL IN WATER EMULSION COMPRISING ANTIFUNGAL TRIAZOLE COMPOUND DISPERSED IN WATER WITH FATTY ACID TRIGLYCERIDE, LECITHIN EMULSIFIER | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-29 | — | — | US | disclosed |
| CN-1106390-A | Azole compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-08-09 | — | — | CN | disclosed |