SCHEMBL867516

SCHEMBL867516

C=COC(=O)/C=C\C(=O)OC

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 3/20 0.65
HCAR2 Q8TDS4 2/20 0.65
KEAP1 Q14145 1/20 0.65
ALDH1A1 P00352 8/20 0.38
MAPT P10636 5/20 0.38
KDM4E B2RXH2 3/20 0.38
TDP1 Q9NUW8 1/20 0.38
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
TYR P14679 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
GFPT1 Q06210 1/20 0.36
ALOX15 P16050 2/20 0.35
HSD17B10 Q99714 2/20 0.35
RECQL P46063 1/20 0.35
LMNA P02545 3/20 0.33
TTR P02766 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3463021 0.98 NFE2L2 (0.62) NFE2L2HCAR2KEAP1ALDH1A1MAPT
Ether SCHEMBL4334029 0.88 HCAR2 (0.50) NFE2L2HCAR2KEAP1ALDH1A1MAPT
SCHEMBL154658 0.87 HCAR2 (0.40) NFE2L2HCAR2KEAP1ALDH1A1MAPT
SCHEMBL169560 0.87 HCAR2 (0.40) NFE2L2HCAR2KEAP1ALDH1A1MAPT
SCHEMBL154657 0.87 HCAR2 (0.40) NFE2L2HCAR2KEAP1ALDH1A1MAPT
Dimethyl Fumarate SCHEMBL4449638 0.86 NFE2L2 (0.59) NFE2L2HCAR2KEAP1ALDH1A1MAPT
Ethylene SCHEMBL28349172 0.84 HCAR2 (0.38) NFE2L2HCAR2KEAP1MAPTLMNA
Dimethyl Maleate SCHEMBL9797077 0.82 NFE2L2 (0.68) NFE2L2HCAR2KEAP1ALDH1A1MAPT
Dimethyl Maleate SCHEMBL25393211 0.81 NFE2L2 (0.77) NFE2L2HCAR2KEAP1ALDH1A1MAPT
Dimethyl Fumarate SCHEMBL20562286 0.81 NFE2L2 (0.87) NFE2L2HCAR2KEAP1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114948885-B Improved abirater acetate Long Nami crystal oral preparation and preparation method thereof 广东西捷药业有限公司 2023-11-28 CN claimed
CN-116456968-A Formulations of somatostatin modulators 克林提克斯医药股份有限公司 2023-07-18 CN claimed
CN-116196285-A Nanometer tadalafil orally disintegrating composition and preparation method and application thereof 广东西捷药业有限公司 2023-06-02 CN claimed
CN-114948885-A Improved abiraterone acetate nanocrystal oral preparation and preparation method thereof 广东西捷药业有限公司 2022-08-30 CN claimed
CN-108373561-A A kind of transparent multiple-factor degradation modification polyethylene film and preparation method thereof 江南大学 2018-08-07 CN claimed
CN-108366993-A Complexes of celecoxib and salts and derivatives thereof, process for their preparation and pharmaceutical compositions containing them 成药技术IP控股有限公司 2018-08-03 CN claimed
CN-108329563-A Degradable polymeric packaging material and preparation method thereof under a kind of natural conditions 高源� 2018-07-27 CN claimed
US-8252296-B2 Aqueous polymer dispersion and use thereof in cosmetics BASF SE (DE) 2012-08-28 US claimed
US-5587272-A TONING LAYER WITH IMAGEWISE TACKY AND NONTACKY AREAS, TRANSFERRING ADHERENT TONER TO TEMPORARY SUPPORT, THEN ONTO IMAGE RECEPTOR, REPEATING FOR DIFFERENT COLORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-12-24 US claimed
US-4519801-A SUSTAINED DRUG RELEASE ALZA CORPORATION (US) 1985-05-28 US claimed
US-4352878-A INCLUSION OF DIHYDRIC ALCOHOL IN COATING COMPOSITION TO RETARD DRYING HITACHI, LTD. (JP) 1982-10-05 US claimed
US-4196271-A 2-CYANOACRYLATE, POLYCARBOXYLIC ACID IMPACT STRENGTH IMPROVER TOAGOSEI CHEMICAL INDUSTRY CO., LTD. (JP) 1980-04-01 US claimed
CN-117769459-A Polymaleic acid-assisted metal nanoparticle synthesis for three-way catalytic applications 庄信万丰股份有限公司 2024-03-26 CN disclosed
CN-117377473-A Use of somatostatin modulators for the treatment of diseases 克林提克斯医药股份有限公司 2024-01-09 CN disclosed
CN-114948885-B Improved abirater acetate Long Nami crystal oral preparation and preparation method thereof 广东西捷药业有限公司 2023-11-28 CN disclosed
WO-2023210363-A1 FLUORESCENT COMPOUND, METHOD FOR PRODUCING FLUORESCENT COMPOUND, AND WATER TREATMENT AGENT COMPOSITION オルガノ株式会社 2023-11-02 WO disclosed
EP-0265916-A2 Denture stabilizing zinc and strontium salts of ave/ma copolymer Richardson-Vicks, Inc. (US) 1988-05-04 EP disclosed
EP-0051919-A1 Emulsion paint and method of painting Berger, Jenson and Nicholson Limited (GB) 1982-05-19 EP disclosed
US-4196271-A 2-CYANOACRYLATE, POLYCARBOXYLIC ACID IMPACT STRENGTH IMPROVER TOAGOSEI CHEMICAL INDUSTRY CO., LTD. (JP) 1980-04-01 US disclosed
EP-0003214-A1 A method of manufacturing glass fibre mats from an aqueous dispersion of glass fibres and a method of forming said dispersion GAF CORPORATION (US) 1979-08-08 EP disclosed