SCHEMBL154657

SCHEMBL154657

C=COC(=O)/C=C\C(=O)OC=C

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.40
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
MAPT P10636 1/20 0.32
CACNA1B Q00975 1/20 0.32
APBA1 Q02410 1/20 0.32
LMNA P02545 1/20 0.32
TSHR P16473 5/20 0.31
ALDH1A1 P00352 5/20 0.31
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
CYP3A4 P08684 1/20 0.31
HSD17B10 Q99714 1/20 0.31
FGFR4 P22455 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL154658 1.00 HCAR2 (0.40) HCAR2KEAP1NFE2L2MAPTCACNA1B
SCHEMBL169560 1.00 HCAR2 (0.40) HCAR2KEAP1NFE2L2MAPTCACNA1B
Ethylene SCHEMBL28349172 0.97 HCAR2 (0.38) HCAR2KEAP1NFE2L2MAPTCACNA1B
SCHEMBL169561 0.89 HCAR2 (0.50) HCAR2KEAP1NFE2L2MAPTLMNA
SCHEMBL169562 0.89 HCAR2 (0.50) HCAR2KEAP1NFE2L2MAPTLMNA
SCHEMBL634425 0.89 HCAR2 (0.50) HCAR2KEAP1NFE2L2MAPTLMNA
Maleic Acid SCHEMBL28963566 0.89 HCAR2 (0.50) HCAR2KEAP1NFE2L2MAPTLMNA
SCHEMBL20563930 0.88 KEAP1 (0.30) HCAR2KEAP1NFE2L2
SCHEMBL867516 0.87 NFE2L2 (0.65) HCAR2KEAP1NFE2L2MAPTLMNA
SCHEMBL4197639 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1010 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116322326-B Polyurea/polyurethane microcapsules 西姆莱斯股份公司 2025-05-02 CN claimed
US-20250137196-A1 HYDROPHOBIC COATING AND METHOD OF APPLICATION TO SUBSTRATES GREEN THEME TECHNOLOGIES, INC. 2025-05-01 US claimed
WO-2025090528-A1 HYDROPHOBIC COATING AND METHOD OF APPLICATION TO SUBSTRATES GREEN THEME TECHNOLOGIES, INC. (US) 2025-05-01 WO claimed
CN-119317481-A Method for preparing microcapsules 西姆莱斯股份公司 2025-01-14 CN claimed
EP-4393581-A2 BIODEGRADABLE POLYUREA/POLYURETHANE MICROCAPSULES Symrise AG (DE) 2024-07-03 EP claimed
EP-4378575-A1 POLYUREA/POLYURETHANE MICROCAPSULES Symrise AG (DE) 2024-06-05 EP claimed
EP-3969165-B1 BIODEGRADABLE POLYUREA/POLYURETHANE MICROCAPSULES SYMRISE AG (DE) 2024-05-15 EP claimed
EP-3969162-B1 POLYUREA/POLYURETHANE MICROCAPSULES SYMRISE AG (DE) 2024-05-08 EP claimed
US-20240033703-A1 Method for Producing Microcapsules AG, SYMRISE (DE) 2024-02-01 US claimed
US-20230313077-A1 Polyurea/Polyurethane Microcapsules SYMRISE AG (DE) 2023-10-05 US claimed
EP-0290131-A2 Acrylic rubber, acrylic rubber composition and cured rubber article thereof JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1988-11-09 EP claimed
US-4632131-A BLENDING TOBACCO, FILLER, FOAMING AGENT, BINDER AND WATER PHILIP MORRIS INCORPORATED (US) 1986-12-30 US claimed
US-4625737-A DRY BLENDING TOBACCO AND FILLER, ADDING BINDER THEN EXTRUSION PHILIP MORRIS INCORPORATED (US) 1986-12-02 US claimed
US-4611039-A Wettable, gas permeable contact lens PRECISION-COSMET CO., INC. (US) 1986-09-09 US claimed
WO-1986000504-A1 FOAMED, EXTRUDED TOBACCO-CONTAINING SMOKING ARTICLES PHILIP MORRIS INCORPORATED (US) 1986-01-30 WO claimed
EP-0167370-A2 Foamed, extruded tobacco-containing smoking articles Philip Morris Products Inc. (US) 1986-01-08 EP claimed
US-4510950-A Foamed, extruded, tobacco-containing smoking article and method of making same PHILIP MORRIS INCORPORATED (US) 1985-04-16 US claimed
US-4489008-A REACTING AMINOALCOHOL WITH CAROBXYL TERMINATED POLYMER THE B. F. GOODRICH COMPANY (US) 1984-12-18 US claimed
WO-1984002636-A1 FOAMED, EXTRUDED, TOBACCO-CONTAINING SMOKING ARTICLE AND METHOD OF MAKING SAME PHILIP MORRIS INC (US) 1984-07-19 WO claimed
EP-0113595-A2 Foamed, extruded, tobacco-containing smoking article and method of making same Philip Morris Products Inc. (US) 1984-07-18 EP claimed