SCHEMBL8675201

SCHEMBL8675201

CCC(C(=O)OOC)c1ccccc1Cl

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 1/20 0.47
KCNQ2 O43526 2/20 0.44
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
ALDH1A1 P00352 3/20 0.38
HTT P42858 2/20 0.38
NOS3 P29474 1/20 0.37
NOS1 P29475 1/20 0.37
NOS2 P35228 1/20 0.37
AOC3 Q16853 1/20 0.36
MAPK1 P28482 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ADRB2 P07550 1/20 0.36
ADRB1 P08588 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8675888 0.88 MEN1 (0.46) CASP1KCNQ2MEN1KMT2ALMNA
SCHEMBL18300370 0.83 ESR1 (0.39) CASP1MEN1KMT2AMAPK1L3MBTL1
SCHEMBL8833604 0.81 KCNQ2 (0.51) CASP1KCNQ2MEN1KMT2ALMNA
SCHEMBL8679370 0.81 CYP2C19 (0.41) ALDH1A1HTT
SCHEMBL30821928 0.78 KCNQ2 (0.50) CASP1KCNQ2MEN1KMT2ALMNA
SCHEMBL9588027 0.78 KCNQ2 (0.49) CASP1KCNQ2MEN1KMT2ALMNA
SCHEMBL1489632 0.78 KCNQ2 (0.50) CASP1KCNQ2MEN1KMT2ALMNA
SCHEMBL27935785 0.78 KCNQ2 (0.49) CASP1KCNQ2MEN1KMT2ALMNA
SCHEMBL29024339 0.77 KDM4E (0.51) MEN1KMT2ALMNAMAPTALDH1A1
SCHEMBL2032138 0.77 KCNQ2 (0.48) CASP1KCNQ2MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5728911-A CATALYTIC SOLUTION COPOLYMERIZATION OF ETHYLENE WITH POLYUNSATURATED MONOMER DSM COPOLYMER, INC. (US) 1998-03-17 US disclosed
EP-0705284-B1 PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE DSM NV (NL) 1997-07-09 EP disclosed
EP-0705284-A1 PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE DSM NV (NL) 1996-04-10 EP disclosed
WO-1995000564-A1 PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE DSM N.V. (NL) 1995-01-05 WO disclosed
EP-0044119-B1 PROCESS FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE STAMICARBON B.V. (NL) 1985-05-29 EP disclosed
US-4435552-A COORDINATION CATALYST CONTAINING HALOACYL COMPOUND STAMICARBON B.V. (NL) 1984-03-06 US disclosed
EP-0044119-A2 Process for the preparation of copolymers of ethylene with at least one other 1-alkene STAMICARBON B.V. (NL) 1982-01-20 EP disclosed