SCHEMBL8833604

SCHEMBL8833604

CCC(C(=O)C(CC)c1ccccc1Cl)c1ccccc1Cl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNQ2 O43526 2/20 0.51
CASP1 P29466 1/20 0.47
ALDH1A1 P00352 1/20 0.44
ADRB2 P07550 2/20 0.43
ADRB1 P08588 2/20 0.43
AOC3 Q16853 1/20 0.43
CYP2D6 P10635 1/20 0.42
NFKB1 P19838 1/20 0.42
HIF1A Q16665 1/20 0.42
NISCH Q9Y2I1 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
BLM P54132 1/20 0.41
ACP3 P15309 1/20 0.41
LMNA P02545 1/20 0.41
HPGD P15428 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TAS1R3 Q7RTX0 1/20 0.40
TAS1R1 Q7RTX1 1/20 0.40
TAS1R2 Q8TE23 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1489632 0.89 KCNQ2 (0.50) KCNQ2CASP1ALDH1A1ADRB2ADRB1
SCHEMBL30821928 0.89 KCNQ2 (0.50) KCNQ2CASP1ALDH1A1ADRB2ADRB1
SCHEMBL9588027 0.89 KCNQ2 (0.49) KCNQ2CASP1ALDH1A1ADRB2ADRB1
SCHEMBL27935785 0.89 KCNQ2 (0.49) KCNQ2CASP1ALDH1A1ADRB2ADRB1
SCHEMBL2032138 0.87 KCNQ2 (0.48) KCNQ2CASP1ALDH1A1ADRB2ADRB1
SCHEMBL27760992 0.84 CASP1 (0.44) KCNQ2CASP1ALDH1A1ADRB2ADRB1
SCHEMBL27559385 0.82 CASP1 (0.43) KCNQ2CASP1ALDH1A1ADRB2ADRB1
SCHEMBL27518364 0.82 HPGD (0.44) KCNQ2CASP1ALDH1A1ADRB2ADRB1
SCHEMBL8675201 0.81 CASP1 (0.47) KCNQ2CASP1ALDH1A1ADRB2ADRB1
SCHEMBL20534707 0.78 MEN1 (0.48) KCNQ2CASP1ALDH1A1ADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5629200-A MICROORGANISM DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1997-05-13 US disclosed