Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 2/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8678301 | 0.89 | MTNR1B (0.50) | MTNR1BPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8675086 | 0.89 | TDP1 (0.55) | MTNR1BPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8674820 | 0.86 | BRD4 (0.53) | MTNR1BPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8676066 | 0.85 | ESR1 (0.52) | MTNR1BPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8676024 | 0.85 | MTNR1B (0.47) | MTNR1BPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8677652 | 0.83 | PTGER1 (0.49) | MTNR1BPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8677570 | 0.83 | PTGER1 (0.57) | MTNR1BPTGER1TDP1 | |
| SCHEMBL8676390 | 0.83 | MTNR1B (0.51) | MTNR1BPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8676387 | 0.82 | PTGER1 (0.62) | PTGER1PTGER4PTGER3PTGER2TDP1 | |
| SCHEMBL8321828 | 0.82 | PTGER1 (0.70) | MTNR1BPTGER1PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |