Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 3/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8676066 | 0.88 | ESR1 (0.52) | PTGER1PTGER4PTGER3PTGER2MTNR1B | |
| SCHEMBL8676387 | 0.88 | PTGER1 (0.62) | PTGER1PTGER4PTGER3PTGER2TDP1 | |
| SCHEMBL8675086 | 0.87 | TDP1 (0.55) | PTGER1PTGER4PTGER3PTGER2MTNR1B | |
| SCHEMBL8677570 | 0.86 | PTGER1 (0.57) | PTGER1MTNR1BTDP1MRGPRX4 | |
| SCHEMBL8678301 | 0.85 | MTNR1B (0.50) | PTGER1PTGER4PTGER3PTGER2MTNR1B | |
| SCHEMBL8675525 | 0.84 | PTGER1 (0.61) | PTGER1PTGER4PTGER3PTGER2TDP1 | |
| SCHEMBL8676076 | 0.84 | MTNR1B (0.47) | PTGER1PTGER4PTGER3PTGER2MTNR1B | |
| SCHEMBL8675232 | 0.83 | MTNR1B (0.48) | PTGER1PTGER4PTGER3PTGER2MTNR1B | |
| SCHEMBL8676390 | 0.83 | MTNR1B (0.51) | PTGER1PTGER4PTGER3PTGER2MTNR1B | |
| SCHEMBL8679914 | 0.83 | MTNR1B (0.53) | PTGER1PTGER4PTGER3PTGER2MTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |