Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8677682 | 0.85 | TDP1 (0.39) | TDP1MAPTMAPK1L3MBTL1BRD4 | |
| SCHEMBL8674678 | 0.72 | HTR1A (0.44) | L3MBTL1RXRAPTGER1PTGER4PTGER3 | |
| SCHEMBL23536852 | 0.69 | ALDH1A1 (0.37) | TDP1MAPTMAPK1L3MBTL1KDM4E | |
| SCHEMBL4770784 | 0.68 | NPC1 (0.38) | MAPTL3MBTL1KDM4EATMALDH1A1 | |
| SCHEMBL8674770 | 0.68 | HTR1A (0.47) | TDP1MAPTL3MBTL1KDM4EPTGER1 | |
| SCHEMBL8323310 | 0.68 | BRD4 (0.51) | TDP1MAPTMAPK1L3MBTL1BRD4 | |
| SCHEMBL27833448 | 0.68 | BRD4 (0.51) | TDP1MAPTMAPK1L3MBTL1BRD4 | |
| SCHEMBL8682572 | 0.68 | BRD4 (0.51) | TDP1MAPTMAPK1L3MBTL1BRD4 | |
| SCHEMBL6676188 | 0.68 | BRD4 (0.51) | TDP1MAPTMAPK1L3MBTL1BRD4 | |
| SCHEMBL5284629 | 0.67 | ALDH1A1 (0.39) | TDP1MAPTMAPK1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |