Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 7/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 7/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PPIA | P62937 | 1/20 | 0.39 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8679046 | 0.88 | PTGER4 (0.48) | PTGER4PTGER2PTGER3PTGER1MRGPRX4 | |
| SCHEMBL8324662 | 0.84 | MRGPRX4 (0.49) | PTGER4PTGER2PTGER3PTGER1MRGPRX4 | |
| SCHEMBL8324660 | 0.84 | MRGPRX4 (0.49) | PTGER4PTGER2PTGER3PTGER1MRGPRX4 | |
| SCHEMBL8675824 | 0.84 | PTGER1 (0.48) | PTGER4PTGER2PTGER3PTGER1HDAC8 | |
| SCHEMBL6072389 | 0.80 | PTGER4 (0.62) | PTGER4PTGER2PTGER3PTGER1MRGPRX4 | |
| SCHEMBL6072384 | 0.80 | PTGER4 (0.62) | PTGER4PTGER2PTGER3PTGER1MRGPRX4 | |
| SCHEMBL8676443 | 0.78 | PTGER1 (0.51) | PTGER4PTGER2PTGER3PTGER1MRGPRX4 | |
| SCHEMBL8675468 | 0.78 | MRGPRX4 (0.47) | PTGER4PTGER2PTGER3PTGER1MRGPRX4 | |
| SCHEMBL8325869 | 0.77 | MRGPRX4 (0.48) | PTGER4PTGER2PTGER3PTGER1MRGPRX4 | |
| SCHEMBL8325865 | 0.77 | MRGPRX4 (0.48) | PTGER4PTGER2PTGER3PTGER1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |