Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 10/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8676663 | 0.87 | PTGER1 (0.50) | PTGER1PTGER4PTGER2PTGER3FOLH1 | |
| SCHEMBL8675466 | 0.84 | PTGER4 (0.46) | PTGER1PTGER4PTGER2PTGER3FOLH1 | |
| SCHEMBL8327587 | 0.83 | RXRA (0.49) | PTGER1PTGER4PTGER2PTGER3FOLH1 | |
| SCHEMBL8327584 | 0.83 | RXRA (0.49) | PTGER1PTGER4PTGER2PTGER3FOLH1 | |
| SCHEMBL8675899 | 0.77 | PTGER1 (0.54) | PTGER1PTGER4PTGER2PTGER3FOLH1 | |
| SCHEMBL16898127 | 0.76 | FOLH1 (0.58) | PTGER1FOLH1ALDH1A1KDM4EPOLB | |
| SCHEMBL8675826 | 0.76 | SLC6A2 (0.46) | PTGER1PTGER4PTGER2PTGER3ALDH1A1 | |
| SCHEMBL8677981 | 0.76 | SGMS2 (0.46) | PTGER1PTGER4PTGER2PTGER3FOLH1 | |
| SCHEMBL8322908 | 0.76 | PTGER4 (0.47) | PTGER1PTGER4PTGER2PTGER3ALDH1A1 | |
| SCHEMBL8322906 | 0.76 | PTGER4 (0.47) | PTGER1PTGER4PTGER2PTGER3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |