Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 5/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.41 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.39 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322416 | 0.88 | MTNR1B (0.55) | MTNR1BMTNR1APTGER1PTGER4PTGER3 | |
| SCHEMBL8675502 | 0.87 | MTNR1B (0.55) | MTNR1BMTNR1APTGER1PTGER4PTGER3 | |
| SCHEMBL8678491 | 0.84 | MTNR1B (0.54) | MTNR1BMTNR1APTGER1PTGER4PTGER3 | |
| SCHEMBL9066724 | 0.81 | BRD4 (0.41) | MTNR1BMTNR1APTGER1PTGER4PTGER3 | |
| SCHEMBL8675664 | 0.81 | MTNR1B (0.51) | MTNR1BMTNR1APTGER1PTGER4PTGER3 | |
| SCHEMBL8326632 | 0.81 | MTNR1B (0.55) | MTNR1BMTNR1APTGER1PTGER4PTGER3 | |
| SCHEMBL9066730 | 0.79 | BRD4 (0.42) | MTNR1BMTNR1APTGER1BRD4SPHK2 | |
| SCHEMBL8678928 | 0.77 | PTGER1 (0.54) | MTNR1BMTNR1APTGER1PTGER4PTGER3 | |
| SCHEMBL8677617 | 0.77 | MTNR1B (0.50) | MTNR1BMTNR1APTGER1PTGER4PTGER3 | |
| SCHEMBL8326066 | 0.76 | PTGER1 (0.48) | MTNR1BMTNR1APTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |