Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 4/20 | 0.51 |
| ▸ | BRD4 | O60885 | 5/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8678491 | 0.91 | MTNR1B (0.54) | MTNR1BBRD4MTNR1APTGER1PTGER4 | |
| SCHEMBL8326520 | 0.90 | MTNR1B (0.56) | MTNR1BBRD4MTNR1APTGER1PTGER4 | |
| SCHEMBL8326518 | 0.90 | MTNR1B (0.56) | MTNR1BBRD4MTNR1APTGER1PTGER4 | |
| SCHEMBL8675663 | 0.88 | MTNR1B (0.55) | MTNR1BBRD4MTNR1APTGER1PTGER4 | |
| SCHEMBL8676020 | 0.86 | PTGER1 (0.54) | MTNR1BMTNR1APTGER1PTGER4PTGER3 | |
| SCHEMBL8675504 | 0.81 | MTNR1B (0.49) | MTNR1BBRD4MTNR1APTGER1PTGER4 | |
| SCHEMBL8321075 | 0.80 | MTNR1B (0.60) | MTNR1BBRD4MTNR1APTGER1PTGER4 | |
| SCHEMBL8324495 | 0.80 | PTGER1 (0.67) | MTNR1BMTNR1APTGER1PTGER4PTGER3 | |
| SCHEMBL8324492 | 0.80 | PTGER1 (0.67) | MTNR1BMTNR1APTGER1PTGER4PTGER3 | |
| SCHEMBL8322870 | 0.79 | PTGER1 (0.55) | MTNR1BMTNR1APTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |