Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674587 | 0.99 | CYSLTR2 (0.36) | NPC1RAB9ACYSLTR2CYSLTR1PNMT | |
| SCHEMBL8677867 | 0.92 | NPC1 (0.36) | NPC1RAB9APNMTMIFHTR7 | |
| SCHEMBL8675078 | 0.82 | CYSLTR2 (0.38) | NPC1RAB9ACYSLTR2CYSLTR1PNMT | |
| SCHEMBL8675951 | 0.77 | PNMT (0.40) | NPC1RAB9ACYSLTR2CYSLTR1PNMT | |
| SCHEMBL27762485 | 0.75 | PNMT (0.43) | NPC1RAB9ACYSLTR2CYSLTR1PNMT | |
| SCHEMBL23777720 | 0.71 | PNMT (0.46) | NPC1RAB9APNMTMIFHTR7 | |
| SCHEMBL20402091 | 0.69 | PAM (0.46) | NPC1RAB9ACYSLTR2CYSLTR1PNMT | |
| SCHEMBL3952483 | 0.69 | PNMT (0.52) | NPC1RAB9APNMTMIFHTR7 | |
| SCHEMBL8528720 | 0.68 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1PNMT | |
| SCHEMBL8528717 | 0.68 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726264-A | ETHYLENE-BRIDGED-METALLOCENE-TRANSITION METAL COMPOUND | PHILLIPS PETROLEUM COMPANY (US) | 1998-03-10 | — | — | US | disclosed |