Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 5/20 | 0.36 |
| ▸ | TUBB | P07437 | 5/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | MDM4 | O15151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8645276 | 0.77 | HSP90AA1 (0.33) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8646870 | 0.76 | HSP90AA1 (0.34) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8661489 | 0.75 | KRAS (0.31) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8649727 | 0.75 | KRAS (0.32) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8642034 | 0.74 | KRAS (0.32) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8642543 | 0.74 | HSP90AA1 (0.35) | PTPN5HSP90AA1CNR2MAPTALDH1A1 | |
| SCHEMBL8645270 | 0.74 | KRAS (0.30) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8643258 | 0.73 | KRAS (0.31) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8642654 | 0.73 | KRAS (0.31) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8649362 | 0.72 | ALDH1A1 (0.32) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750558-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1998-05-12 | — | — | US | disclosed |