Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 7/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323718 | 0.84 | MRGPRX4 (0.53) | HTR1ADRD2PTGER1MRGPRX4MAOB | |
| SCHEMBL6215963 | 0.82 | MAOB (0.60) | MRGPRX4MAOB | |
| SCHEMBL8318509 | 0.81 | MRGPRX4 (0.43) | PTGER1MRGPRX4MAOB | |
| SCHEMBL8676539 | 0.80 | PTGER1 (0.44) | PTGER1MRGPRX4NPC1ALDH1A1RAB9A | |
| SCHEMBL4720248 | 0.80 | PTGER1 (0.52) | PTGER1MRGPRX4STAT3 | |
| SCHEMBL693828 | 0.78 | PTGER1 (0.53) | HTR1ADRD2PTGER1STAT3KMT2A | |
| SCHEMBL2954443 | 0.78 | MAPT (0.60) | PTGER1MRGPRX4 | |
| SCHEMBL8676535 | 0.77 | PTGER1 (0.43) | PTGER1MRGPRX4STAT3KMT2A | |
| SCHEMBL8677039 | 0.77 | MRGPRX4 (0.64) | PTGER1MRGPRX4 | |
| SCHEMBL30557975 | 0.76 | PTGER1 (0.54) | PTGER1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |