Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 13/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360278 | 0.80 | HTR1A (0.43) | PTGER1MRGPRX4 | |
| SCHEMBL8318509 | 0.78 | MRGPRX4 (0.43) | PTGER1MRGPRX4 | |
| SCHEMBL8675658 | 0.77 | HTR1A (0.49) | PTGER1STAT3MRGPRX4KMT2A | |
| SCHEMBL8323718 | 0.76 | MRGPRX4 (0.53) | PTGER1MRGPRX4KMT2A | |
| SCHEMBL8678841 | 0.75 | PTGER1 (0.47) | PTGER1MRGPRX4 | |
| SCHEMBL4720248 | 0.72 | PTGER1 (0.52) | PTGER1STAT3MRGPRX4 | |
| SCHEMBL693828 | 0.71 | PTGER1 (0.53) | PTGER1STAT3KMT2A | |
| SCHEMBL8676539 | 0.71 | PTGER1 (0.44) | PTGER1MRGPRX4 | |
| SCHEMBL8677078 | 0.71 | PTGER1 (0.44) | PTGER1 | |
| SCHEMBL9356557 | 0.71 | CYP3A4 (0.44) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |