Acrylic Acid Ethyl Ester

Acrylic Acid Ethyl Ester

SCHEMBL867566

C=C(C)C(=O)OC.C=C(C)C(=O)OCC.C=CC(=O)OCC.CN(C)C

nearest known ligand 0.47

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Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
THRB P10828 2/20 0.41
TSHR P16473 10/20 0.40
NPSR1 Q6W5P4 1/20 0.40
HPGD P15428 1/20 0.39
GLO1 Q04760 1/20 0.36
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
TP53 P04637 2/20 0.34
HIF1A Q16665 2/20 0.34
CYP3A4 P08684 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CYP2C9 P11712 1/20 0.34
MAPT P10636 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid Ethyl Ester SCHEMBL146754 0.98 ALDH1A1 (0.46) ALDH1A1THRBTSHRNPSR1HPGD
Acrylic Acid Ethyl Ester SCHEMBL12100197 0.97 ALDH1A1 (0.50) ALDH1A1THRBTSHRNPSR1HPGD
Acrylic Acid Ethyl Ester SCHEMBL27884650 0.97 ALDH1A1 (0.50) ALDH1A1THRBTSHRNPSR1HPGD
Acrylic Acid Ethyl Ester SCHEMBL7201294 0.95 ALDH1A1 (0.48) ALDH1A1THRBTSHRNPSR1HPGD
Acrylic Acid Ethyl Ester SCHEMBL2370487 0.95 ALDH1A1 (0.52) ALDH1A1THRBTSHRNPSR1HPGD
Acrylic Acid Ethyl Ester SCHEMBL28001077 0.92 ALDH1A1 (0.46) ALDH1A1THRBTSHRNPSR1HPGD
Acrylic Acid Ethyl Ester SCHEMBL27625183 0.92 THRB (0.44) ALDH1A1THRBTSHRNPSR1HPGD
Acrylic Acid Ethyl Ester SCHEMBL9342721 0.92 ALDH1A1 (0.56) ALDH1A1THRBTSHRNPSR1HPGD
Acrylic Acid Ethyl Ester SCHEMBL2097752 0.92 ALDH1A1 (0.56) ALDH1A1THRBTSHRNPSR1HPGD
Acrylic Acid Ethyl Ester SCHEMBL5959889 0.92 ALDH1A1 (0.56) ALDH1A1THRBTSHRNPSR1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024058093-A1 TIMED-RELEASE GRANULES AND USE THEREOF 東和薬品株式会社 2024-03-21 WO disclosed
EP-2654735-B1 RAPIDLY DISINTEGRATING, SOLID COATED DOSAGE FORM BASF SE (DE) 2016-04-13 EP disclosed
US-8715729-B2 Rapidly disintegrating, solid coated dosage form BASF SE (DE) 2014-05-06 US disclosed
EP-2654735-A2 RAPIDLY DISINTEGRATING, SOLID COATED DOSAGE FORM BASF SE (DE) 2013-10-30 EP disclosed
US-20120164223-A1 RAPIDLY DISINTEGRATING, SOLID COATED DOSAGE FORM BASF SE (DE) 2012-06-28 US disclosed
WO-2012085043-A2 RAPIDLY DISINTEGRATING, SOLID COATED DOSAGE FORM BASF SE (DE) 2012-06-28 WO disclosed
US-20120076858-A1 Orally Disintegrating Dosage Forms Containing Taste-Masked Active Ingredients BASF SE (DE) 2012-03-29 US disclosed
US-20110014286-A1 MIXTURE FOR PRODUCING RAPIDLY DISINTEGRATING TABLETS SUDZUCKER AKTIENGESELLSCHAFT MANNHEIM/OCHSENFURT (DE) 2011-01-20 US disclosed