Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 19/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8672609 | 0.88 | GRM5 (0.47) | GRM5 | |
| SCHEMBL28811006 | 0.88 | GRM5 (0.47) | GRM5 | |
| SCHEMBL14995149 | 0.81 | GRM5 (0.70) | GRM5 | |
| SCHEMBL2892482 | 0.79 | GRM5 (0.43) | GRM5MEN1KMT2A | |
| SCHEMBL2285672 | 0.79 | GRM5 (0.42) | GRM5 | |
| SCHEMBL2290995 | 0.76 | GRM5 (0.44) | GRM5MEN1KMT2A | |
| SCHEMBL15004308 | 0.76 | GRM5 (0.44) | GRM5KMT2A | |
| SCHEMBL5090735 | 0.76 | GRM5 (0.43) | GRM5 | |
| SCHEMBL4536276 | 0.76 | GRM5 (0.40) | GRM5 | |
| SCHEMBL4048946 | 0.76 | GRM5 (0.42) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880512-A1 | NOVEL AROMATIC PIPERAZINES DERIVED FROM SUBSTITUTED CYCLOAZANES, METHOD FOR PREPARING SAME, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997028141-A1 | NOVEL AROMATIC PIPERAZINES DERIVED FROM SUBSTITUTED CYCLOAZANES, METHOD FOR PREPARING SAME, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1997-08-07 | — | — | WO | disclosed |