Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1165021 | 0.86 | ALDH1A1 (0.44) | ALDH1A1ALOX15SLC2A1GAATNF | |
| SCHEMBL28579723 | 0.84 | DPP4 (0.40) | ALDH1A1DPP4SLC2A1GAATNF | |
| SCHEMBL21956736 | 0.83 | ALDH1A1 (0.52) | ALDH1A1DPP4ALOX15SLC2A1GAA | |
| SCHEMBL1358784 | 0.83 | DPP4 (0.54) | ALDH1A1DPP4ALOX15SLC2A1GAA | |
| SCHEMBL27630874 | 0.83 | ALDH1A1 (0.46) | ALDH1A1DPP4ALOX15SLC2A1GAA | |
| SCHEMBL1313390 | 0.81 | ALDH1A1 (0.61) | ALDH1A1DPP4GAAKDM4EHSD17B10 | |
| SCHEMBL29181700 | 0.81 | DPP4 (0.52) | ALDH1A1DPP4ALOX15SLC2A1GAA | |
| Potassium SCHEMBL30811378 | 0.81 | DPP4 (0.52) | ALDH1A1DPP4ALOX15SLC2A1GAA | |
| SCHEMBL8676513 | 0.81 | PBRM1 (0.43) | ALDH1A1DPP4SLC2A1GAACXCR2 | |
| SCHEMBL30553986 | 0.81 | DPP4 (0.38) | ALDH1A1DPP4SLC2A1GAATNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824817-A | Herbicidal compositions based on 2,6-dichloro-3-fluoro-benzonitrile, and new intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-20 | — | — | US | claimed |
| US-20250333406-A1 | SULFONYL CYCLIC DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | LYSOWAY THERAPEUTICS INC (US) | 2025-10-30 | — | — | US | disclosed |
| WO-2023235305-A2 | SULFONYL CYCLIC DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | Lysoway Therapeutics, Inc. (US) | 2023-12-07 | — | — | WO | disclosed |
| CN-110156770-B | Aminopyridine derivatives as inhibitors of TAM family kinases | 圣诺康生命科学公司 | 2022-10-04 | — | — | CN | disclosed |
| US-11034686-B2 | Aminopyridine derivatives as TAM family kinase inhibitors | SIGNALCHEM LIFESCIENCES CORPORATION (CA) | 2021-06-15 | — | — | US | disclosed |
| US-11034685-B2 | Aminopyridine derivatives as TAM family kinase inhibitors | SIGNALCHEM LIFESCIENCES CORPORATION (CA) | 2021-06-15 | — | — | US | disclosed |
| US-20200299288-A1 | AMINOPYRIDINE DERIVATIVES AS TAM FAMILY KINASE INHIBITORS | SIGNALCHEM LIFESCIENCES CORPORATION (CA) | 2020-09-24 | — | — | US | disclosed |
| US-20200299287-A1 | AMINOPYRIDINE DERIVATIVES AS TAM FAMILY KINASE INHIBITORS | SIGNALCHEM LIFESCIENCES CORPORATION (CA) | 2020-09-24 | — | — | US | disclosed |
| US-10723725-B2 | Aminopyridine derivatives as TAM family kinase inhibitors | SIGNALCHEM LIFESCIENCES CORPORATION (CA) | 2020-07-28 | — | — | US | disclosed |
| EP-3074390-B1 | AMINOPYRIDINE DERIVATIVES AS TAM FAMILY KINASE INHIBITORS | SIGNALCHEM LIFESCIENCES CORP (CA) | 2020-07-08 | — | — | EP | disclosed |
| CN-110156770-A | Aminopyrazole derivatives as TAM race kinase inhibitor | 圣诺康生命科学公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-105764514-B | Aminopyridine derivatives as inhibitors of TAM family kinases | 圣诺康生命科学公司 | 2019-07-12 | — | — | CN | disclosed |
| US-20190152965-A1 | AMINOPYRIDINE DERIVATIVES AS TAM FAMILY KINASE INHIBITORS | SIGNALCHEM LIFESCIENCES CORPORATION (CA) | 2019-05-23 | — | — | US | disclosed |
| US-10233176-B2 | Aminopyridine derivatives as TAM family kinase inhibitors | SIGNALCHEM LIFESCIENCES CORPORATION (CA) | 2019-03-19 | — | — | US | disclosed |
| US-20170022189-A1 | AMINOPYRIDINE DERIVATIVES AS TAM FAMILY KINASE INHIBITORS | SIGNALCHEM LIFESCIENCES CORPORATION (CA) | 2017-01-26 | — | — | US | disclosed |
| EP-3074390-A2 | AMINOPYRIDINE DERIVATIVES AS TAM FAMILY KINASE INHIBITORS | SignalChem Lifesciences Corporation (CA) | 2016-10-05 | — | — | EP | disclosed |
| CN-105764514-A | Aminopyridine derivatives as inhibitors of TAM family kinases | 圣诺康生命科学公司 | 2016-07-13 | — | — | CN | disclosed |
| WO-2015081257-A2 | AMINOPYRIDINE DERIVATIVES AS TAM FAMILY KINASE INHIBITORS | SIGNALCHEM LIFESCIENCES CORPORATION (CA) | 2015-06-04 | — | — | WO | disclosed |
| US-5824817-A | Herbicidal compositions based on 2,6-dichloro-3-fluoro-benzonitrile, and new intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200299287-A1 | AMINOPYRIDINE DERIVATIVES AS TAM FAMILY KINASE INHIBITORS | MAP3K6, MAP3K5, MERTK | ALDH1A1 3357/4885DPP4 1395/4885ALOX15 4486/4885 |
| US-10723725-B2 | Aminopyridine derivatives as TAM family kinase inhibitors | MAP3K6, MAP3K5, MERTK | ALDH1A1 3357/4885DPP4 1395/4885ALOX15 4486/4885 |
| US-11034685-B2 | Aminopyridine derivatives as TAM family kinase inhibitors | MAP3K6, MAP3K5, MERTK | ALDH1A1 3357/4885DPP4 1395/4885ALOX15 4486/4885 |
| US-11034686-B2 | Aminopyridine derivatives as TAM family kinase inhibitors | MAP3K6, MAP3K5, MERTK | ALDH1A1 3357/4885DPP4 1395/4885ALOX15 4486/4885 |
| US-10233176-B2 | Aminopyridine derivatives as TAM family kinase inhibitors | MAP3K6, MAP3K5, MERTK | ALDH1A1 3357/4885DPP4 1395/4885ALOX15 4486/4885 |
| US-20200299288-A1 | AMINOPYRIDINE DERIVATIVES AS TAM FAMILY KINASE INHIBITORS | MAP3K6, MAP3K5, MERTK | ALDH1A1 3357/4885DPP4 1395/4885ALOX15 4486/4885 |
| US-20170022189-A1 | AMINOPYRIDINE DERIVATIVES AS TAM FAMILY KINASE INHIBITORS | MAP3K6, MAP3K5, MERTK | ALDH1A1 3357/4885DPP4 1395/4885ALOX15 4486/4885 |
| US-20190152965-A1 | AMINOPYRIDINE DERIVATIVES AS TAM FAMILY KINASE INHIBITORS | MAP3K6, MAP3K5, MERTK | ALDH1A1 3357/4885DPP4 1395/4885ALOX15 4486/4885 |
| US-20250333406-A1 | SULFONYL CYCLIC DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | STOML2, ATP2A3, ATP2A1 | ALDH1A1 3204/4885DPP4 552/4885ALOX15 3108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.