Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.54 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.48 |
| ▸ | RXRA | P19793 | 3/20 | 0.46 |
| ▸ | RXRB | P28702 | 3/20 | 0.46 |
| ▸ | RXRG | P48443 | 3/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | CYP26B1 | Q9NR63 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674842 | 0.83 | RXRA (0.68) | PPARGCYP26A1RXRARXRBRXRG | |
| SCHEMBL8675471 | 0.82 | MAOB (0.53) | PPARG | |
| SCHEMBL8677714 | 0.82 | PPARG (0.53) | PPARGCYP26A1RXRARXRBRXRG | |
| SCHEMBL8676448 | 0.79 | RARA (0.56) | PPARGCYP26A1RXRARXRBRXRG | |
| SCHEMBL9272893 | 0.79 | MAOB (0.49) | PPARGCYP26A1RXRARXRBRXRG | |
| SCHEMBL8675711 | 0.78 | PPARG (0.50) | PPARGCYP26A1RXRARXRBRXRG | |
| SCHEMBL8674612 | 0.76 | MAOB (0.56) | PPARGCYP3A4 | |
| SCHEMBL10435472 | 0.75 | PPARG (0.47) | PPARGCYP26A1RXRARXRBRXRG | |
| SCHEMBL1395785 | 0.75 | PARP10 (0.68) | PARP10 | |
| SCHEMBL8676840 | 0.75 | RXRB (0.71) | CYP26A1RXRARXRBRXRGCYP26B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739374-A | Processes of preparing diphenylheteroalkyl derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1998-04-14 | — | — | US | disclosed |
| US-5656619-A | Diphenylheteroalkyl derivatives, the preparation thereof and drugs and cosmetics prepared therefrom | BASF AKTIENGESELLSCHAFT (DE) | 1997-08-12 | — | — | US | disclosed |
| US-5527945-A | Diphenylheteroalkyl derivatives, the preparation thereof and drugs and cosmetics prepared therefrom | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-18 | — | — | US | disclosed |
| US-5248823-A | Diphenylheteroalkyl derivatives, the preparation thereof and drugs and cosmetics prepared therefrom | BASF AKTIENGESELLSCHAFT (DE) | 1993-09-28 | — | — | US | disclosed |
| US-5225601-A | Sulfur containing compounds for skin disorders | BASF AKTIENGESELLSCHAFT (DE) | 1993-07-06 | — | — | US | disclosed |