Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.64 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.64 |
| ▸ | DRD2 | P14416 | 4/20 | 0.59 |
| ▸ | DRD4 | P21917 | 3/20 | 0.59 |
| ▸ | DRD3 | P35462 | 3/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | HTR1B | P28222 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7938726 | 0.99 | CHRM2 (0.63) | CHRM2CHRM1CHRM3DRD2DRD4 | |
| SCHEMBL8925229 | 0.92 | DRD2 (0.67) | CHRM2CHRM1CHRM3DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL7938677 | 0.87 | CHRM2 (0.65) | CHRM2CHRM1CHRM3DRD2DRD4 | |
| SCHEMBL8892571 | 0.83 | DRD2 (0.82) | CHRM2CHRM1CHRM3DRD2DRD4 | |
| SCHEMBL2218622 | 0.81 | DRD2 (0.82) | CHRM2CHRM1CHRM3DRD2DRD4 | |
| SCHEMBL9558839 | 0.81 | CHRM2 (0.68) | CHRM2CHRM1CHRM3DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL9355015 | 0.80 | DRD2 (0.81) | DRD2DRD4DRD3HTR1AHTR1D | |
| SCHEMBL7926554 | 0.80 | CHRM2 (0.66) | CHRM2CHRM1CHRM3DRD2DRD4 | |
| SCHEMBL7031018 | 0.79 | DRD2 (0.71) | CHRM2CHRM1CHRM3DRD2DRD4 | |
| SCHEMBL8893091 | 0.79 | DRD2 (0.74) | CHRM2CHRM1CHRM3DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2785879-B2 | — | — | 1998-08-13 | — | — | JP | claimed |
| EP-0476016-A1 | THERAPEUTICALLY USEFUL 2-AMINOTETRALIN DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 1992-03-25 | — | — | EP | claimed |
| WO-1990015047-A1 | THERAPEUTICALLY USEFUL 2-AMINOTETRALIN DERIVATIVES | THE UPJOHN COMPANY (US) | 1990-12-13 | — | — | WO | claimed |