Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.67 |
| ▸ | DRD4 | P21917 | 1/20 | 0.67 |
| ▸ | DRD3 | P35462 | 1/20 | 0.67 |
| ▸ | HTR1A | P08908 | 2/20 | 0.63 |
| ▸ | HTR1D | P28221 | 1/20 | 0.63 |
| ▸ | HTR1B | P28222 | 1/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8675787 | 0.92 | CHRM2 (0.64) | DRD2DRD4DRD3HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL7938726 | 0.90 | CHRM2 (0.63) | DRD2DRD4DRD3HTR1AHTR1D | |
| SCHEMBL2218622 | 0.89 | DRD2 (0.82) | DRD2DRD4DRD3HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL9355015 | 0.88 | DRD2 (0.81) | DRD2DRD4DRD3HTR1AHTR1D | |
| SCHEMBL8893091 | 0.87 | DRD2 (0.74) | DRD2DRD4DRD3HTR1AHTR1D | |
| SCHEMBL9032366 | 0.85 | HTR1A (0.79) | DRD2DRD4DRD3HTR1AHTR1D | |
| SCHEMBL8891564 | 0.84 | DRD2 (0.75) | DRD2DRD4DRD3HTR1AHTR1D | |
| SCHEMBL9558117 | 0.83 | DRD2 (0.70) | DRD2DRD4DRD3HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL7938677 | 0.82 | CHRM2 (0.65) | DRD2DRD4DRD3CHRM2CHRM1 | |
| SCHEMBL3732774 | 0.81 | DRD2 (0.85) | DRD2DRD4DRD3HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5690906-A | TETRALIN DERIVATIVES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1997-11-25 | — | — | US | disclosed |