Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.55 |
| ▸ | DRD2 | P14416 | 3/20 | 0.55 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | CFD | P00746 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | F11 | P03951 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8675094 | 0.99 | HTR1A (0.54) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL8674870 | 0.86 | HTR1A (0.56) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL8677030 | 0.85 | ABCB1 (0.56) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL8676722 | 0.85 | HTR1A (0.55) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL8677215 | 0.85 | ALDH1A1 (0.58) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL8676623 | 0.82 | HTR1A (0.51) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL8674773 | 0.82 | HTR1A (0.60) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL8676619 | 0.80 | BRD4 (0.62) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL8675205 | 0.79 | PTGER1 (0.71) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL8675521 | 0.79 | PTGER1 (0.67) | HTR1ADRD2PTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |