Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5369005 | 0.92 | THRB (0.46) | THRBTSHRALDH1A1CA1CA2 | |
| SCHEMBL11323191 | 0.84 | THRB (0.41) | THRBTSHRALDH1A1 | |
| SCHEMBL11504218 | 0.81 | THRB (0.37) | THRBTSHRALDH1A1 | |
| SCHEMBL8677312 | 0.81 | TSHR (0.40) | THRBTSHRALDH1A1 | |
| SCHEMBL11530639 | 0.79 | THRB (0.46) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL11527930 | 0.75 | THRB (0.46) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL17029722 | 0.75 | THRB (0.39) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL5366993 | 0.73 | THRB (0.42) | THRBTSHRALDH1A1 | |
| SCHEMBL235038 | 0.73 | THRB (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL12860038 | 0.73 | THRB (0.50) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4376844-A | STORAGE STABILITY | ROHM AND HAAS COMPANY (US) | 1983-03-15 | — | — | US | claimed |
| US-4331793-A | UNSATURATED GLYCIDYL MONOMER, OXAZOLIDINYL OR OXAZINYLALKYL ACRYLATE | ROHM AND HAAS COMPANY (US) | 1982-05-25 | — | — | US | claimed |
| US-4308356-A | Hydrocurable ambient curing polyepoxide coating and adhesive compositions and method of using same | ROHM AND HAAS COMPANY (US) | 1981-12-29 | — | — | US | claimed |
| US-5840806-A | COMPOSITION COMPRISING RESIN FORMED BY CONDENSATION OF POLYSILOXANE WITH POLYMER HAVING HYDROLYZABLE SILYL GROUP AND ADDITIONAL FUNCTIONAL GROUP, COMPOUND CAPABLE OF REACTING WITH SAID GROUP | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1998-11-24 | — | — | US | disclosed |
| US-4373008-A | Ambient hydrocurable coating compositions | ROHM AND HAAS COMPANY (US) | 1983-02-08 | — | — | US | disclosed |
| US-4299867-A | ACRYLIC POLYMER OF AN OXAZOLIDINE FUNCTIONAL MONOMER AND AN UNSATURATED ESTER | ROHM AND HAAS COMPANY (US) | 1981-11-10 | — | — | US | disclosed |
| EP-0034720-A2 | Hydrocurable compositions comprising substituted oxazolidine or oxazine polymer and poly acryloxy compound, and their use in coatings, impregnants and adhesives | ROHM AND HAAS COMPANY (US) | 1981-09-02 | — | — | EP | disclosed |