Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8675820 | 0.79 | THRB (0.40) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL9230252 | 0.78 | THRB (0.42) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL17029722 | 0.78 | THRB (0.39) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL11744218 | 0.77 | THRB (0.41) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL235038 | 0.76 | THRB (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL327201 | 0.76 | THRB (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL12860038 | 0.76 | THRB (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL6142874 | 0.73 | THRB (0.74) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL15636 | 0.73 | THRB (0.74) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL68168 | 0.73 | THRB (0.47) | THRBTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148981-A | Dithiophosphorylated copolymers of aziridineethyl acrylates or methacrylates and alkyl acrylates or methacrylates | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1979-04-10 | — | — | US | claimed |