Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 4/20 | 0.41 |
| ▸ | FNTB | P49356 | 4/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.39 |
| ▸ | ITGAV | P06756 | 3/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 3/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8676384 | 0.85 | GPR132 (0.43) | FNTAFNTB | |
| SCHEMBL8679794 | 0.85 | PPARG (0.43) | FNTAFNTBGRM2TDP1L3MBTL1 | |
| SCHEMBL8679534 | 0.84 | PTPN1 (0.46) | FNTAFNTBITGB3ITGB1ITGAV | |
| SCHEMBL8561807 | 0.84 | TDP1 (0.48) | FNTAFNTBITGB3ITGB1ITGAV | |
| SCHEMBL8679817 | 0.84 | GRM2 (0.43) | GRM2ITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL8677140 | 0.83 | SRD5A2 (0.45) | FNTAFNTBGRM2ITGB3TDP1 | |
| SCHEMBL8676560 | 0.83 | FNTA (0.41) | FNTAFNTBITGB1TDP1L3MBTL1 | |
| SCHEMBL8678019 | 0.83 | PPARG (0.45) | FNTAFNTBGRM2TDP1L3MBTL1 | |
| SCHEMBL8678028 | 0.83 | GRM2 (0.45) | GRM2ITGB3PTGESALOX5PPARG | |
| SCHEMBL8678794 | 0.82 | GRM2 (0.47) | GRM2ITGB3ITGB1PTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753641-A | SYNERGISTIC THERAPY COMPRISING FINASTERIDE AND TERAZOSIN DRUGS | MERCK & CO., INC. (US) | 1998-05-19 | — | — | US | disclosed |