Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8679534 | 0.91 | PTPN1 (0.46) | PPARGFNTAFNTBMAPTCYP2C9 | |
| SCHEMBL8677140 | 0.91 | SRD5A2 (0.45) | PPARGFNTAFNTBMAPTCYP2C9 | |
| SCHEMBL8679794 | 0.90 | PPARG (0.43) | PPARGFNTAFNTBMAPTCYP2C9 | |
| SCHEMBL8676560 | 0.89 | FNTA (0.41) | FNTAFNTBMAPTCYP2C9CYP2C19 | |
| SCHEMBL8676384 | 0.85 | GPR132 (0.43) | FNTAFNTB | |
| SCHEMBL8676266 | 0.85 | FNTA (0.38) | FNTAFNTBMAPTCYP2C9CYP2C19 | |
| SCHEMBL8675834 | 0.83 | FNTA (0.41) | PPARGFNTAFNTBTDP1L3MBTL1 | |
| SCHEMBL8676357 | 0.83 | SRD5A2 (0.59) | PPARGGRM2SRD5A2 | |
| SCHEMBL8679817 | 0.83 | GRM2 (0.43) | PPARGGRM2 | |
| SCHEMBL8678028 | 0.82 | GRM2 (0.45) | PPARGGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753641-A | SYNERGISTIC THERAPY COMPRISING FINASTERIDE AND TERAZOSIN DRUGS | MERCK & CO., INC. (US) | 1998-05-19 | — | — | US | disclosed |