Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 4/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PPARD | Q03181 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8679798 | 0.86 | MAPT (0.43) | L3MBTL1NPSR1MAPTTDP1CYP2C9 | |
| SCHEMBL8676389 | 0.85 | LRRK2 (0.43) | L3MBTL1NPSR1MAPTTDP1CYP2C9 | |
| SCHEMBL8675846 | 0.84 | SLC22A12 (0.40) | L3MBTL1NPSR1SGMS2SLC22A12MAPT | |
| SCHEMBL8676564 | 0.84 | MAPT (0.42) | L3MBTL1NPSR1MAPTTDP1CYP2C9 | |
| SCHEMBL8679538 | 0.84 | L3MBTL1 (0.42) | L3MBTL1NPSR1MAPTTDP1CYP2C9 | |
| SCHEMBL8679819 | 0.82 | PPARG (0.42) | L3MBTL1NPSR1CXCR2PPARAPPARG | |
| SCHEMBL8678023 | 0.82 | L3MBTL1 (0.40) | L3MBTL1NPSR1MAPTTDP1CYP2C9 | |
| SCHEMBL8677142 | 0.82 | SRD5A2 (0.43) | L3MBTL1NPSR1MAPTTDP1CYP2C9 | |
| SCHEMBL8561805 | 0.82 | NPSR1 (0.48) | L3MBTL1NPSR1MAPTTDP1CYP2C9 | |
| SCHEMBL8678032 | 0.82 | CXCR2 (0.44) | L3MBTL1NPSR1CXCR2PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753641-A | SYNERGISTIC THERAPY COMPRISING FINASTERIDE AND TERAZOSIN DRUGS | MERCK & CO., INC. (US) | 1998-05-19 | — | — | US | disclosed |