Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 4/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8679538 | 0.92 | L3MBTL1 (0.42) | MAPTL3MBTL1SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL8676564 | 0.92 | MAPT (0.42) | MAPTL3MBTL1SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL8677142 | 0.90 | SRD5A2 (0.43) | MAPTL3MBTL1SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL8678023 | 0.90 | L3MBTL1 (0.40) | MAPTL3MBTL1SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL8676389 | 0.87 | LRRK2 (0.43) | MAPTL3MBTL1SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL8676269 | 0.87 | L3MBTL1 (0.38) | MAPTL3MBTL1SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL8675844 | 0.86 | L3MBTL1 (0.40) | MAPTL3MBTL1SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL8679819 | 0.84 | PPARG (0.42) | L3MBTL1PPARGNPSR1CXCR2PPARA | |
| SCHEMBL8679799 | 0.84 | MAPT (0.42) | MAPTL3MBTL1SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL8678032 | 0.84 | CXCR2 (0.44) | L3MBTL1PPARGNPSR1CXCR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753641-A | SYNERGISTIC THERAPY COMPRISING FINASTERIDE AND TERAZOSIN DRUGS | MERCK & CO., INC. (US) | 1998-05-19 | — | — | US | disclosed |