Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 6/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 6/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 6/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 6/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.34 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.34 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.34 |
| ▸ | GRIK4 | Q16099 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8675850 | 1.00 | SLC18A3 (0.35) | SLC18A3GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8677797 | 0.85 | CA12 (0.41) | SLC18A3PARP1MAPT | |
| SCHEMBL8677801 | 0.85 | CA12 (0.41) | SLC18A3PARP1MAPT | |
| SCHEMBL8674860 | 0.79 | GRIA1 (0.53) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8674862 | 0.79 | GRIA1 (0.53) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8611338 | 0.79 | OPRL1 (0.52) | PARP1OPRM1OPRL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8674801 | 0.76 | GRIA1 (0.56) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7190464 | 0.69 | ALDH1A1 (0.45) | PARP1OPRM1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7190455 | 0.69 | ALDH1A1 (0.45) | PARP1OPRM1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7190460 | 0.69 | ALDH1A1 (0.45) | PARP1OPRM1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849743-A | Quinoxalines and drugs prepared therefrom | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| WO-1996019476-A1 | NOVEL QUINOXALINES AND DRUGS PREPARED THEREFROM | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-27 | — | — | WO | disclosed |