Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8677801 | 1.00 | CA12 (0.41) | CA12CA9PARP1MAPTTDP1 | |
| SCHEMBL8675854 | 0.85 | SLC18A3 (0.35) | PARP1MAPTSLC18A3 | |
| SCHEMBL8675850 | 0.85 | SLC18A3 (0.35) | PARP1MAPTSLC18A3 | |
| SCHEMBL8609291 | 0.80 | OPRL1 (0.48) | CA12CA9PARP1 | |
| SCHEMBL8676782 | 0.79 | ALDH1A1 (0.43) | CA12CA9PARP1MAPTSLC18A3 | |
| SCHEMBL8674860 | 0.76 | GRIA1 (0.53) | — | |
| SCHEMBL8674862 | 0.76 | GRIA1 (0.53) | — | |
| SCHEMBL8674799 | 0.73 | GRIA1 (0.56) | — | |
| SCHEMBL8674801 | 0.73 | GRIA1 (0.56) | — | |
| SCHEMBL8593265 | 0.72 | CA12 (0.48) | CA12CA9PARP1MAPTAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849743-A | Quinoxalines and drugs prepared therefrom | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |