Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8676997 | 0.97 | ALDH1A1 (0.43) | ALDH1A1KDM4EPKMTSHRADORA3 | |
| SCHEMBL8677539 | 0.95 | MAPT (0.43) | ALDH1A1KDM4EPKMTSHRADORA3 | |
| SCHEMBL8827914 | 0.89 | ALDH1A1 (0.38) | ALDH1A1HPGDHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL8678772 | 0.89 | ADORA3 (0.42) | ALDH1A1KDM4EPKMTSHRADORA3 | |
| SCHEMBL8677612 | 0.88 | ADORA3 (0.41) | ALDH1A1KDM4EPKMTSHRADORA3 | |
| SCHEMBL8827945 | 0.87 | ESR1 (0.40) | ALDH1A1HPGDHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL8827929 | 0.85 | GRIA1 (0.39) | ALDH1A1MAPTSMN1; SMN2LMNAATM | |
| SCHEMBL8677205 | 0.82 | PRKDC (0.45) | ALDH1A1KDM4EADORA3HPGDHSD17B10 | |
| SCHEMBL8827923 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL8827939 | 0.78 | ALDH1A1 (0.40) | ALDH1A1KDM4ETSHRHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750708-A | Pyridine compounds intermediates processes compositions and methods | ELI LILLY AND COMPANY (US) | 1998-05-12 | — | — | US | disclosed |
| US-5672609-A | POSTMENOPAUSAL SYNDROME; ANTILIPEMIC AND -CARCINOGENIC AGENTS; OSTEOPOROSIS; CARDIOTONIC AGENTS; RESTENOSIS; SIDE EFFECT REDUCTION COMPARED TO ESTROGEN | ELI LILLY AND COMPANY (US) | 1997-09-30 | — | — | US | disclosed |